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Croscarmellose

CAS 74811-65-7 · 20/100 · High conf.

Also registered as 1 other CAS number

357172-57-7

Concern score

20/100Minor concern based on regulatory listings.
High confidence

Croscarmellose in plain language

What it is

Also known as Croscarmellose sodium · Cross-linked sodium carboxy methyl cellulose · Crosslinked carboxymethyl cellulose · Ac-Di-Sol SD 411NF · Ac-Di-Sol SD 711 · Ac-Di-Sol SDW 802NF

Show all 10 names

Cross carboxymethyl cellulose sodium · Primellose · Sodium croscarmellose · Vivasol

What it does

Used in consumer products as a thickener.

  • Thickener
Is it a concern?
Minor concern: no hazard classifications on record.

Why it's flagged

EPA CPDat observed this chemical in 25 composition records across product categories including Personal care, Food and drug.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Croscarmellose appears in these published regulatory listings.

  • Inactive ingredient in US drugs

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Pharma
  • Food
  • EUEFSAEFSA opinionRe-evaluation of celluloses E 460(i), E 460(ii), E 461, E 462, E 463, E 464, E 465, E 466, E 468 and E 469 as food additives (EFSA ANS)
    • Re-evaluation of celluloses E 460(i), E 460(ii), E 461, E 462, E 463, E 464, E 465, E 466, E 468 and E 469 as food additives (EFSA ANS)Source →
  • GLOBALJECFAEvaluatedJECFA evaluation record.
  • USEPAcommercial use observedEPA CPDat observed this chemical in 25 composition records across product categories including Personal care, Food and drug. EPA CPDat classifies this chemical for functional uses including Filler, Thickening agent.
    • EPA CPDat observed this chemical in 25 composition records across product categories including Personal care, Food and drug. EPA CPDat classifies this chemical for functional uses including Filler, Thickening agent.Source →
  • USFDAinactive ingredient databaseRoute: ORAL; Dosage form: TABLET; Maximum daily exposure: 80 mg
    • Route: ORAL; Dosage form: TABLET; Maximum daily exposure: 80 mgSource →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as polymer.
    • openFDA substance registry classifies this ingredient as polymer.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

  • JECFA

    Joint FAO/WHO Expert Committee on Food Additives

  • EFSA

    European Food Safety Authority

    • Re-evaluation of celluloses E 460(i), E 460(ii), E 461, E 462, E 463, E 464, E 465, E 466, E 468 and E 469 as food additives (EFSA ANS)

      2018 · EU EFSA listing · Read the source →

Evidence & sources

No graded research studies for Croscarmellose yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • EFSA OpenFoodTox

    regulatory · updated 2026-10-04

    Open →

  • EPA Chemical and Products Database

    exposure · updated July 2013

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA Inactive Ingredient Database

    regulatory · updated 2026-01-09

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • WHO JECFA Database

    regulatory · updated 2026-10-04

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed Croscarmellose in a product composition. These are source records, not Greenveil catalog products.

Source records

25

Named organisations

5

Personal careFood and drug

Typical roles

Thickener
See products using Croscarmellose →

Catalog

Found in these products

Their ingredient lists include Croscarmellose; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 252 →Find products without it →

Co-occurrence

Often appears with

Ingredients that frequently appear alongside Croscarmellose in the catalog.