What does Protein kinase inhibitor H89 do?

Used in cosmetics as a skin-conditioning agent and a bleaching agent.

Is Protein kinase inhibitor H89 safe?

We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

beauty
industrial

Protein kinase inhibitor H89

CAS 1000995-75-4

Also registered as 1 other CAS number

127243-85-0

Protein kinase inhibitor H89 chemical structure

Concern score

Not assessed — no hazard data yet.

Protein kinase inhibitor H89 in plain language

What it is: On cosmetic ingredient lists it appears as “Bromophenyl propenaminoethyl isoquinolinesulfonamide hcl”.
Also known as Bromophenyl propenaminoethyl isoquinolinesulfonamide hcl · H-89 · 1ydt · H 89 (pharmaceutical) · H89 · N-(2-(4-BROMOCINNAMYLAMINO)ETHYL)-5-ISOQUINOLINESULFONAMIDE
Show all 7 names
Protein kinase inhibitor H-89
What it does: Used in cosmetics as a skin-conditioning agent and a bleaching agent.
Skin conditioning
Bleaching
Is it a concern?: We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. Protein kinase inhibitor H89 appears in these published regulatory listings.

Recorded in these product areas

Found in consumer products
Industrial

EUCosIngActiveBromophenyl Propenaminoethyl Isoquinolinesulfonamide HCl is the organic compound that conforms to the formula
- Bromophenyl Propenaminoethyl Isoquinolinesulfonamide HCl is the organic compound that conforms to the formulaSource →
USEPAcommercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products.
- EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Protein kinase inhibitor H89. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.

Evidence & sources

No graded research studies for Protein kinase inhibitor H89 yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

6 data sources

Where this comes from

CosIng
regulatory · updated 2026-09-23
Open →
EPA Chemical and Products Database
exposure · updated 2020-08-31
Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
Open →
FDA GSRS UNII
registry · updated 2026-02-26
Open →
openFDA Substance
registry · updated 2026-05-24
Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Where it has been recorded

How often EPA CPDat has listed Protein kinase inhibitor H89 in a product composition. These are source records, not Greenveil catalog products.

Named organisations

Typical roles

Skin conditioningBleaching

See products using Protein kinase inhibitor H89 →