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  • food

Hydroxysafflor yellow a

CAS 120478-62-8 · 80/100 · High conf.

Also registered as 5 other CAS numbers

855782-18-2 · 1423072-23-4 · 78281-02-4 · 146087-19-6 · 664361-78-8

Concern score

80/100Critical concern based on regulatory listings.
High confidence

Hydroxysafflor yellow a in plain language

What it is

Also known as Carthamus yellow · Hsya · Safflomin a

What it does

Used in food as a colour.

  • Colour
Is it a concern?
Critical concern: no hazard classifications on record.

Why it's flagged

EPA DSSTox provides the canonical identifier, structure, and synonym profile for this chemical.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Hydroxysafflor yellow a appears in these published regulatory listings.

  • GLOBALJECFANO ADI ALLOCATEDJECFA evaluation lists ADI NO ADI ALLOCATED. Functional class: colour.
    • JECFA evaluation lists ADI NO ADI ALLOCATED. Functional class: colour.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

  • JECFA

    Joint FAO/WHO Expert Committee on Food Additives

    • JECFA evaluation lists ADI NO ADI ALLOCATED. Functional class: colour.

      Year not recorded · GLOBAL JECFA listing · Read the source →

  • EFSA

    European Food Safety Authority

    No EFSA opinion on file.

Evidence & sources

No graded research studies for Hydroxysafflor yellow a yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

4 data sources

Where this comes from

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • WHO JECFA Database

    regulatory · updated 2026-10-04

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →
Reference links (1)
Openfda substance

J. Nat. Prod. 2013, 76, 2, 270–274 Publication Date:February 6, 2013 https://doi.org/10.1021/np300814k

Read →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.