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Diisopropanolamine

CAS 1335-54-2

Also registered as 2 other CAS numbers

1141787-00-9 · 110-97-4

Diisopropanolamine chemical structure

Concern score

Not assessed — no hazard data yet.

Diisopropanolamine in plain language

What it is

Also known as 1,1'-Azanediyldi(propan-2-ol) · 1-(2-hydroxypropylamino)propan-2-ol · BIS(2-PROPANOL)AMINE · Di-isopropanolamine · 1,1'-IMINODI-2-PROPANOL · 1,1'-Iminobis(2-propanol)

Show all 17 names

1,1'-iminodipropan-2-ol · 1,1'-iminodipropane-2-ol · 110924 DR DI-Isopropanolamine · 2,2'-DIHYDROXYDIPROPYLAMIN · 2-Propanol, 1,1'-iminobis- · 2-Propanol, 1,1'-iminodi- · BIS(2-HYDROXYPROPYL)AMINE · DIPA (alcohol) · Di-2-propanolamine · Dipropyl-2,2'-dihydroxy-amine · N,N-Bis(2-hydroxypropyl)amine

What it does

Used in cosmetics as a pH buffer.

  • Buffering
  • Emulsifier
  • Chelating agent
  • pH adjuster
  • Stabiliser
  • Cleaning agent
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. Diisopropanolamine appears in these published regulatory listings.

  • Inactive ingredient in US drugs

Recorded in these product areas

  • Found in consumer products
  • Cleaning
  • Pharma
  • Food
  • Industrial
  • USFDAinactive ingredient database3 entries
    • Route: TOPICAL; Dosage form: CREAM; Maximum daily exposure: 10 mgSource →
    • Route: TOPICAL; Dosage form: GEL; Potency: 1.5 %w/wSource →
    • Route: TOPICAL; Dosage form: SOLUTION; Potency: ADJ PHSource →
  • EUCosIngActiveRestriction: II/411
  • USEPAcommercial use observedEPA CPDat observed this chemical in 45 composition records across product categories including Cleaning and safety, Industrial products, Food and drug. EPA CPDat classifies this chemical for functional uses including pH regulating agent, Stabilizing agent, Cleaning agent.
    • EPA CPDat observed this chemical in 45 composition records across product categories including Cleaning and safety, Industrial products, Food and drug. EPA CPDat classifies this chemical for functional uses including pH regulating agent, Stabilizing agent, Cleaning agent.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Diisopropanolamine. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Diisopropanolamine yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EPA Chemical and Products Database

    exposure · updated January 7, 2008

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA Inactive Ingredient Database

    regulatory · updated 2026-01-09

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Where it has been recorded

How often EPA CPDat has listed Diisopropanolamine in a product composition. These are source records, not Greenveil catalog products.

Source records

45

Named organisations

6

Cleaning and safetyIndustrial productsFood and drugLaboratory suppliesHome maintenanceCleaning products and household care

Typical roles

BufferingEmulsifierChelating agentpH adjusterStabiliserCleaning agent
See products using Diisopropanolamine →

Catalog

Found in these products

Cosmetic and personal-care products that list Diisopropanolamine are shown first. Their ingredient lists include Diisopropanolamine; each product's own rating depends on its whole formula, so it is shown on the product page, not here.