beauty
cleaning
pharma

Phytosphingosine

CAS 388566-94-7

Also registered as 3 other CAS numbers

33511-66-9 · 947747-32-2 · 554-62-1

Concern score

Not assessed — no hazard data yet.

Phytosphingosine in plain language

What it is: Also known as (+)-d-ribo-phytosphingosine · (2S,3S,4R)-2-Aminooctadecane-1,3,4-triol · 1,3,4-OCTADECANETRIOL, 2-AMINO-, d-ribo- · 4-D-HYDROXYSPHINGANINE · C18-PHYTOSPHINGOSINE · D-RIBO-1,3,4-TRIHYDROXY-2-AMINOOCTADECANE
Show all 17 names
D-ribo-phytosphingosine · Sphinganine, 4-D-HYDROXY · (2S,3S,4R)-2-Amino-1,3,4-octadecanetriol · 1,3,4-Octadecanetriol, 2-amino-, (2S, 3S, 4R)- · 4-R-hydroxyoctadecasphinganine · 4R-hydroxysphinganine · Biomide ps · C18H39NO3 · Cytomide pgs · Ds-phytosphingosine · N-Dodecanoyl-NBD-phytosphingosine
What it does: Used in cosmetics as a skin-conditioning agent and a hair conditioner.
Skin conditioning
Hair conditioning
Conditioner
Is it a concern?: We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. Phytosphingosine appears in these published regulatory listings.

In marketed US drugs

Recorded in these product areas

Found in consumer products
Beauty
Cleaning

EUCosIngActiveListed in CosIng inventory for cosmetic use.
- Listed in CosIng inventory for cosmetic use.Source →
USEPAcommercial use observedEPA CPDat observed this chemical in 402 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Softener and conditioner.
- EPA CPDat observed this chemical in 402 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Softener and conditioner.Source →
USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 2 active drug products and 2 total products.
- FDA NDC lists this ingredient in 2 active drug products and 2 total products.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Phytosphingosine. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.

Evidence & sources

No graded research studies for Phytosphingosine yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

CosIng
regulatory · updated 2026-09-23
Open →
EPA Chemical and Products Database
exposure · updated September 2019
Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
Open →
FDA National Drug Code Directory
regulatory · updated 2026-12-31
Open →
FDA GSRS UNII
registry · updated 2026-02-26
Open →
openFDA Substance
registry · updated 2026-05-24
Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Where it has been recorded

How often EPA CPDat has listed Phytosphingosine in a product composition. These are source records, not Greenveil catalog products.

Source records

402

Named organisations

Personal care

Typical roles

Skin conditioningHair conditioningConditioner

See products using Phytosphingosine →

Catalog

Found in these products

Their ingredient lists include Phytosphingosine; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 142 →Find products without it →