What does Isonicotinic acid do?

Used in cosmetics as a skin-conditioning agent.

Is Isonicotinic acid safe?

We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

beauty
industrial

Isonicotinic acid

CAS 163751-04-0

Also registered as 2 other CAS numbers

1580002-27-2 · 55-22-1

Concern score

Not assessed — no hazard data yet.

Isonicotinic acid in plain language

What it is: On cosmetic ingredient lists it appears as “Isoniacin”.
Also known as Isoniacin · Acide iso-nicotinique · .gamma.-picolinic acid · .gamma.-pyridinecarboxylic acid · Pyridine-4-carboxylic acid · 1,4-Dihydroisonicotinic acid
Show all 14 names
4-Carboxypyridine · 4-Picolinic acid · 4-Pyridinecarboxylic acid · 4-Pyridylcarboxylic acid · Acide isonicotinique · Isonicotinsaure · acido isonicotinico · p-Pyridinecarboxylic acid
What it does: Used in cosmetics as a skin-conditioning agent.
Skin conditioning
Is it a concern?: We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. Isonicotinic acid appears in these published regulatory listings.

Recorded in these product areas

Found in consumer products
Industrial

EUCosIngActiveIsoniacin is the organic compound that conforms to the formula
- Isoniacin is the organic compound that conforms to the formulaSource →
USEPAcommercial use observedEPA CPDat observed this chemical in 5 composition records across product categories including Laboratory supplies.
- EPA CPDat observed this chemical in 5 composition records across product categories including Laboratory supplies.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Isonicotinic acid. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.

Evidence & sources

No graded research studies for Isonicotinic acid yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

6 data sources

Where this comes from

CosIng
regulatory · updated 2026-09-23
Open →
EPA Chemical and Products Database
exposure · updated 2019-02-27
Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
Open →
FDA GSRS UNII
registry · updated 2026-02-26
Open →
openFDA Substance
registry · updated 2026-05-24
Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Where it has been recorded

How often EPA CPDat has listed Isonicotinic acid in a product composition. These are source records, not Greenveil catalog products.

Source records

Laboratory supplies

Typical roles

Skin conditioning

See products using Isonicotinic acid →