# N-Nitrosopyrrolidine

URL: https://app.greenveil.ai/ingredients/ingredient_dtxsid_dtxsid8021062
Categories: food, industrial
Identifier: DTXSID8021062

> N-Nitrosopyrrolidine. Greenveil chemical-concern score: 100/100 — Critical concern based on regulatory listings.. Compiled from 6 published data sources.

## Safety assessment

- Chemical concern score: 100/100 — Critical concern based on regulatory listings.
- Confidence in this assessment: High
- Is it a concern? Critical concern: no hazard classifications on record.
- Rationale: EPA CPDat observed this chemical in 1 composition records across product categories including Laboratory supplies.

## Regulatory status

- EU: EFSA opinion — Re-evaluation of potassium nitrite (E 249) and sodium nitrite (E 250) as food additives (EFSA ANS)
- US: commercial use observed — EPA CPDat observed this chemical in 1 composition records across product categories including Laboratory supplies.
- US: listed in openFDA substance — openFDA substance registry classifies this ingredient as chemical.

## Expert safety opinions

- JECFA (Joint FAO/WHO Expert Committee on Food Additives): no opinion on file.
- EFSA (European Food Safety Authority): Re-evaluation of potassium nitrite (E 249) and sodium nitrite (E 250) as food additives (EFSA ANS) — 2017 — https://doi.org/10.2903/j.efsa.2017.4786.

## Data sources

- EFSA OpenFoodTox (updated 2026-10-04): https://doi.org/10.5281/zenodo.8120114
- EPA Chemical and Products Database (updated March 8, 2019): http://siri.org/msds/f1/btm/btmfs.html
- EPA DSSTox Identifiers (updated 2025-12-29): https://epa.figshare.com/articles/dataset/Chemistry_Dashboard_Data_DSSTox_Identifiers_Mapped_to_CAS_Numbers_and_Names/5588566
- FDA GSRS UNII (updated 2026-02-26): https://precision.fda.gov/uniisearch/
- openFDA Substance (updated 2026-05-24): https://api.fda.gov/other/substance.json?search=unii:SZ4J5WK201
- PubChem Live Enrichment (updated 2026-05-17): https://pubchem.ncbi.nlm.nih.gov/compound/13591

_Assessed by Greenveil._