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  • beauty
  • cleaning
  • food
  • industrial

Benzocaine

CAS 71123-91-6

Also registered as 2 other CAS numbers

1865741-16-7 · 94-09-7

Benzocaine chemical structure

Concern score

Not assessed — no hazard data yet.

Benzocaine in plain language

What it is

On cosmetic ingredient lists it appears as “Ethyl PABA”.

Also known as Ethyl PABA · Ethyl aminobenzoate · Benzoic acid, 4-AMINO-, ethyl ester · Ethyl p-aminobenzoate · Ethyl para-amino benzoate · Ethyl 4-aminobenzoate

Show all 36 names

Parathesine · (p-(Ethoxycarbonyl)phenylamine · 4-(Ethoxycarbonyl)aniline · 4-(Ethoxycarbonyl)phenylamine · 4-AMINOBENZOIC acid ethyl ester · Americaine · Anaesthesin · AR-01 · AR01 · Amben ethyl ester · Anaesthin · Anesthesin · Anesthesine · Anesthone · Baby anbesol · Benzoate, 4-AMINO-, ethyl · Dermoplast · Et-PABA · Flavamed · Hurricaine · Identhesin · Norcaine · Norcain · Orthesin · Parathesin · Subcutin · Solu H · Topcaine · p-amino benzosyre ethyl ester (anaesthesin) · Auralgan component benzocaine

What it does

Used in cosmetics as a UV filter and an oral-care ingredient.

  • UV absorber
  • Oral care
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. Benzocaine appears in these published regulatory listings.

  • In marketed US drugs
  • Inactive ingredient in US drugs

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Cleaning
  • Pharma
  • Food
  • Industrial
  • EUCosIngActiveRestriction: II/167
  • USEPAcommercial use observedEPA CPDat observed this chemical in 80 composition records across product categories including Personal care, Food and drug, Medical/dental. EPA CPDat classifies this chemical for functional uses including anti-irritant, Pharmaceutical, Active - topical anesthetic.
    • EPA CPDat observed this chemical in 80 composition records across product categories including Personal care, Food and drug, Medical/dental. EPA CPDat classifies this chemical for functional uses including anti-irritant, Pharmaceutical, Active - topical anesthetic.Source →
  • USFDAinactive ingredient databaseRoute: TOPICAL; Dosage form: OINTMENT; Potency: 1 %w/w
    • Route: TOPICAL; Dosage form: OINTMENT; Potency: 1 %w/wSource →
  • USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 564 active drug products and 579 total products.
    • FDA NDC lists this ingredient in 564 active drug products and 579 total products.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Benzocaine. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Benzocaine yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

8 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

  • EPA Chemical and Products Database

    exposure · updated January 7, 2008

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA Inactive Ingredient Database

    regulatory · updated 2026-01-09

    Open →

  • FDA National Drug Code Directory

    regulatory · updated 2027-12-31

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →
Reference links (2)
Openfda substance

adisinsight.springer.com

Read →
Openfda substance

clinicaltrialsregister.eu

Read →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Where it has been recorded

How often FDA National Drug Code directory has listed Benzocaine in a product composition. These are source records, not Greenveil catalog products.

Source records

579

Typical roles

UV absorberOral care
See products using Benzocaine →