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Dibasic potassium phosphate

CAS 7558-11-4 · 0/100 · High conf.

Also registered as 3 other CAS numbers

60704-91-8 · 2260985-76-8 · 7758-11-4

Dibasic potassium phosphate chemical structure

Concern score

0/100Low concern — well-established and permitted without restriction (FDA GRAS; CIR safe when formulated as directed; EU CosIng).
High confidence

Dibasic potassium phosphate in plain language

What it is

On cosmetic ingredient lists it appears as “Dipotassium phosphate”.

Also known as Dipotassium phosphate · Potassium phosphate · Potassium phosphate dibasic · Dipotassium acid phosphate · Dipotassium hydrogen phosphate · Dipotassium monophosphate

Show all 29 names

Secondary potassium phosphate · Dipotassium hydrogen phosphate (K2HPO4) · Dipotassium salt phosphoric acid · Phosphoric acid, potassium salt (1:2) · Potassium phosphate (K2HPO4) · Potassium phosphate dibasic anhydrate · Conclyte P · Di-potassium hydrogen phosphate · Dipotassium hydrogen monophosphate · Dikaliumhydrogenorthophosphat · Dipotassium Hydrogenphosphate · Dipotassium hydrogen orthophosphate · Dipotassium hydrogenorthophosphate · Dipotassium monohydrogen phosphate · Dipotassium orthophosphate · E-340(II) · Hydrogen dipotassium phosphate · Ins NO.340(II) · INS-340(II) · Potassium dibasic phosphate · Potassium monophosphate · Kali phosphoricum · Potassium phosphates component dibasic potassium phosphate

What it does

Used in cosmetics as an anticorrosive and a pH buffer.

  • Anticorrosive
  • Buffering
  • Yeast food, acidity regulator, sequestrant
  • Emulsifier
  • Chelating agent
  • pH adjuster
Is it a concern?
Low concern: no hazard classifications on record. It is listed for cosmetic use in the EU.

Why it's flagged

EPA CPDat observed this chemical in 310 composition records across product categories including Construction and building materials, Specialty occupational products, Vehicle.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Dibasic potassium phosphate appears in these published regulatory listings.

  • In marketed US drugs
  • Inactive ingredient in US drugs

Recorded in these product areas

  • Found in consumer products
  • Cleaning
  • Industrial
  • USFDAinactive ingredient database8 entries — 4 administration routes
    • Route: ORAL; Dosage form: CAPSULE; Potency: 30 mgSource →
    • Route: ORAL; Dosage form: SOLUTION; Maximum daily exposure: 890 mgSource →
    • Route: ORAL; Dosage form: SUSPENSION; Maximum daily exposure: 24 mgSource →
    • Route: ORAL; Dosage form: SYRUP; Potency: 22 mg/5mlSource →
    • Route: ORAL; Dosage form: TABLET; Potency: NASource →
    • Route: SUBCUTANEOUS; Dosage form: INJECTION; Potency: 13.6 mgSource →
    • Route: INTRAMUSCULAR; Dosage form: INJECTION; Potency: 0.6 %w/vSource →
    • Route: INTRA-ARTICULAR; Dosage form: INJECTION; Potency: 0.6 %w/vSource →
  • GLOBALJECFAEvaluated2 entries
    • JECFA evaluation record. Functional class: yeast food, acidity regulator, sequestrant.Source →
    • JECFA evaluation record.Source →
  • USFDAmarketed drug occurrence2 entries
    • FDA NDC lists this ingredient in 159 active drug products and 175 total products.Source →
    • FDA NDC lists this ingredient in 128 active drug products and 130 total products.Source →
  • EUCosIngActiveListed in CosIng inventory for cosmetic use.
    • Listed in CosIng inventory for cosmetic use.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 310 composition records across product categories including Construction and building materials, Specialty occupational products, Vehicle. EPA CPDat classifies this chemical for functional uses including pH regulating agent, Corrosion inhibitor, Flavouring and nutrient.
    • EPA CPDat observed this chemical in 310 composition records across product categories including Construction and building materials, Specialty occupational products, Vehicle. EPA CPDat classifies this chemical for functional uses including pH regulating agent, Corrosion inhibitor, Flavouring and nutrient.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

  • JECFA

    Joint FAO/WHO Expert Committee on Food Additives

    • JECFA evaluation record. Functional class: yeast food, acidity regulator, sequestrant.

      Year not recorded · GLOBAL JECFA listing · Read the source →

    • JECFA evaluation record.

      Year not recorded · GLOBAL JECFA listing · Read the source →

Evidence & sources

No graded research studies for Dibasic potassium phosphate yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

9 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EPA Chemical and Products Database

    exposure · updated september 17, 2016

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA Inactive Ingredient Database

    regulatory · updated 2026-01-09

    Open →
  • FDA National Drug Code Directory

    regulatory · updated 2029-07-08

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • WHO JECFA Database

    regulatory · updated 2026-10-04

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →
Reference links (3)
Openfda substance

drugs-about.com

Openfda substance

accessdata.fda.gov

Openfda substance

codexalimentarius.net

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed Dibasic potassium phosphate in a product composition. These are source records, not Greenveil catalog products.

Source records

310

Named organisations

6

Construction and building materialsSpecialty occupational productsVehicleLaboratory suppliesIndustrial productsConstruction

Typical roles

AnticorrosiveBufferingYeast food, acidity regulator, sequestrantEmulsifierChelating agentpH adjuster
See products using Dibasic potassium phosphate →

Catalog

Found in these products

Their ingredient lists include Dibasic potassium phosphate; each product's own rating depends on its whole formula, so it is shown on the product page, not here.