What does Diltiazem hcl do?

Used in cosmetics as an astringent and a skin protectant.

Is Diltiazem hcl safe?

We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

beauty
food
pharma

Diltiazem hcl

CAS 38411-61-9

Also registered as 2 other CAS numbers

103532-26-9 · 33286-22-5

Concern score

Not assessed — no hazard data yet.

Diltiazem hcl in plain language

What it is: Also known as Diltiazem hydrochloride · Cartia · Diltzac · Taztia · Adizem · Altiazem
Show all 27 names
Britiazim · Cardizem · CRD-401 · Cardizem CD · Cardizem LA · Cardizem SR · Cartia XT · Deltazen · Dilacor · Diladel · Dilpral · Dilrene · Dilzem · Dilzene · Masdil · QT Drugs · Rg 83606 · Tiazac · Tildiem · Taztia XT · Zilden
What it does: Used in cosmetics as an astringent and a skin protectant.
Astringent
Skin protecting
Is it a concern?: We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. Diltiazem hcl appears in these published regulatory listings.

In marketed US drugs

Recorded in these product areas

Found in consumer products
Pharma
Food

USFDAmarketed drug occurrence2 entries
- FDA NDC lists this ingredient in 1 active drug products and 1 total products.Source →
- FDA NDC lists this ingredient in 290 active drug products and 290 total products.Source →
EUCosIngActiveDiltiazem HCl is the organic compound that conforms to the formula
- Diltiazem HCl is the organic compound that conforms to the formulaSource →
USEPAcommercial use observedEPA CPDat observed this chemical in 3 composition records across product categories including Food and drug.
- EPA CPDat observed this chemical in 3 composition records across product categories including Food and drug.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Diltiazem hcl. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.

Evidence & sources

No graded research studies for Diltiazem hcl yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

CosIng
regulatory · updated 2026-09-23
Open →
EPA Chemical and Products Database
exposure · updated March 8, 2019
Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
Open →
FDA National Drug Code Directory
regulatory · updated 2026-12-31
Open →
FDA GSRS UNII
registry · updated 2026-02-26
Open →
openFDA Substance
registry · updated 2026-05-24
Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Open →

Reference links (1)

Openfda substance

mc.usp.org

Read →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Where it has been recorded

How often EPA CPDat has listed Diltiazem hcl in a product composition. These are source records, not Greenveil catalog products.

Source records

Named organisations

Food and drug

Typical roles

AstringentSkin protecting

See products using Diltiazem hcl →