# DILTIAZEM HCL

URL: https://app.greenveil.ai/ingredients/ingredient_dtxsid_dtxsid8040147
Categories: beauty, food, pharma
Functions: Astringent, Skin protecting
Identifier: DTXSID8040147

> DILTIAZEM HCL: Used in cosmetics as an astringent and a skin protectant. EPA CPDat observed this chemical in 3 composition records across product categories including Food and drug. Compiled from 7 published data sources.

## Safety assessment

- Chemical concern: not yet assessed
- Is it a concern? We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
- Rationale: EPA CPDat observed this chemical in 3 composition records across product categories including Food and drug.

## Regulatory status

- EU: Active — Diltiazem HCl is the organic compound that conforms to the formula
- US: commercial use observed — EPA CPDat observed this chemical in 3 composition records across product categories including Food and drug.
- US: listed in openFDA substance — openFDA substance registry classifies this ingredient as chemical.
- US: marketed drug occurrence — FDA NDC lists this ingredient in 1 active drug products and 1 total products.
- US: marketed drug occurrence — FDA NDC lists this ingredient in 290 active drug products and 290 total products.

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/100300
- EPA Chemical and Products Database (updated March 8, 2019): http://siri.org/msds/f2/bvs/bvsqx.html
- EPA DSSTox Identifiers (updated 2025-12-29): https://epa.figshare.com/articles/dataset/Chemistry_Dashboard_Data_DSSTox_Identifiers_Mapped_to_CAS_Numbers_and_Names/5588566
- FDA National Drug Code Directory (updated 2026-12-31): https://www.fda.gov/drugs/drug-approvals-and-databases/national-drug-code-directory-support-files
- FDA GSRS UNII (updated 2026-02-26): https://precision.fda.gov/uniisearch/
- openFDA Substance (updated 2026-05-24): https://api.fda.gov/other/substance.json?search=unii:OLH94387TE
- PubChem Live Enrichment (updated 2026-05-17): https://pubchem.ncbi.nlm.nih.gov/compound/62920

_Assessed by Greenveil._