# TROLAMINE

URL: https://app.greenveil.ai/ingredients/ingredient_dtxsid_dtxsid9021392
Categories: beauty, cleaning, food, industrial, pharma
Functions: Emulsifying, Cleansing, Buffering, Fragrance, Colourant, Emulsifier
Identifier: DTXSID9021392

> TROLAMINE: Used in cosmetics as an emulsifier, a cleansing agent and a pH buffer. Greenveil chemical-concern score: 20/100 — Minor concern based on regulatory listings.. Compiled from 9 published data sources.

## Safety assessment

- Chemical concern score: 20/100 — Minor concern based on regulatory listings.
- Confidence in this assessment: High
- Is it a concern? Minor concern: no hazard classifications on record. It is listed for cosmetic use in the EU.
- Rationale: EPA CPDat observed this chemical in 6487 composition records across product categories including Construction and building materials, Furniture and furnishings, Cleaning products and household care.

## Regulatory status

- EU: Active — Restriction: III/62
- EU: EFSA opinion — Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request related to a 17th list of substances for food contact materials (EFSA AFC)
- US: commercial use observed — EPA CPDat observed this chemical in 6487 composition records across product categories including Construction and building materials, Furniture and furnishings, Cleaning products and household care. EPA CPDat classifies this chemical for functional uses including pH regulating agent, Cleaning agent, Surfactant (surface active agent).
- US: inactive ingredient database — Route: NASAL; Dosage form: DROPS; Potency: NA
- US: inactive ingredient database — Route: NASAL; Dosage form: SOLUTION; Potency: NA
- US: inactive ingredient database — Route: NASAL; Dosage form: SPRAY; Potency: NA
- US: inactive ingredient database — Route: RECTAL; Dosage form: AEROSOL, METERED; Potency: ADJ PH
- US: inactive ingredient database — Route: TOPICAL; Dosage form: AEROSOL, FOAM; Potency: 2.6 %w/w
- US: inactive ingredient database — Route: TOPICAL; Dosage form: CREAM; Potency: 1 %w/w
- US: inactive ingredient database — Route: TOPICAL; Dosage form: CREAM, AUGMENTED; Maximum daily exposure: 20 mg
- US: inactive ingredient database — Route: TOPICAL; Dosage form: EMULSION; Potency: 0.5 %w/w
- US: inactive ingredient database — Route: TOPICAL; Dosage form: GEL; Maximum daily exposure: 6 mg
- US: inactive ingredient database — Route: TOPICAL; Dosage form: GEL, METERED; Maximum daily exposure: 19 mg
- US: inactive ingredient database — Route: TOPICAL; Dosage form: LIQUID; Potency: NA
- US: inactive ingredient database — Route: INTRAVENOUS; Dosage form: INJECTION, POWDER, FOR SUSPENSION; Potency: 0.02 %w/v
- US: inactive ingredient database — Route: TOPICAL; Dosage form: POWDER; Potency: 0.02 mg/mg
- US: inactive ingredient database — Route: TOPICAL; Dosage form: SHAMPOO; Potency: 3.7 %w/w
- US: inactive ingredient database — Route: TOPICAL; Dosage form: SOAP; Potency: 0.08 %w/w
- US: inactive ingredient database — Route: TOPICAL; Dosage form: SOLUTION; Potency: NA
- US: inactive ingredient database — Route: TOPICAL; Dosage form: SPONGE; Potency: 11 %w/w
- US: inactive ingredient database — Route: TRANSDERMAL; Dosage form: GEL; Maximum daily exposure: 6 mg
- US: inactive ingredient database — Route: TRANSDERMAL; Dosage form: GEL, METERED; Maximum daily exposure: 14 mg
- US: inactive ingredient database — Route: VAGINAL; Dosage form: AEROSOL, FOAM; Potency: 2 %w/w
- US: inactive ingredient database — Route: VAGINAL; Dosage form: CREAM; Maximum daily exposure: 56 mg
- US: marketed drug occurrence — FDA NDC lists this ingredient in 1 active drug products and 4 total products.
- US: listed in openFDA substance — openFDA substance registry classifies this ingredient as chemical.
- US: inactive ingredient database — Route: TOPICAL; Dosage form: LOTION; Maximum daily exposure: 360 mg

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.
- EFSA (European Food Safety Authority): Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request related to a 17th list of substances for food contact materials (EFSA AFC) — 2008 — https://doi.org/10.2903/j.efsa.2008.601.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/38702
- EFSA OpenFoodTox (updated 2026-10-04): https://doi.org/10.5281/zenodo.8120114
- EPA Chemical and Products Database (updated september 9, 2014): https://living-future.org/declare-products/fiberglass-windows/
- EPA DSSTox Identifiers (updated 2025-12-29): https://epa.figshare.com/articles/dataset/Chemistry_Dashboard_Data_DSSTox_Identifiers_Mapped_to_CAS_Numbers_and_Names/5588566
- FDA Inactive Ingredient Database (updated 2026-01-09): https://www.fda.gov/drugs/drug-approvals-and-databases/inactive-ingredients-database-download
- FDA National Drug Code Directory (updated 2028-01-16): https://www.fda.gov/drugs/drug-approvals-and-databases/national-drug-code-directory-support-files
- FDA GSRS UNII (updated 2026-02-26): https://precision.fda.gov/uniisearch/
- openFDA Substance (updated 2026-05-24): https://api.fda.gov/other/substance.json?search=unii:9O3K93S3TK
- PubChem Live Enrichment (updated 2026-05-17): https://pubchem.ncbi.nlm.nih.gov/compound/7618

_Assessed by Greenveil._