# POLYSORBATE 60

URL: https://app.greenveil.ai/ingredients/ingredient_dtxsid_dtxsid9029300
Categories: beauty, cleaning, food, industrial, pharma
Functions: Emulsifying, Cleansing, Emulsifier, Surfactant, Thickener, Fragrance
Identifier: DTXSID9029300

> POLYSORBATE 60: Used in cosmetics as an emulsifier and a cleansing agent. EPA CPDat observed this chemical in 2422 composition records across product categories including Personal care, Cleaning and safety, Food and drug. Compiled from 8 published data sources.

## Safety assessment

- Chemical concern: not yet assessed
- Is it a concern? We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
- Rationale: EPA CPDat observed this chemical in 2422 composition records across product categories including Personal care, Cleaning and safety, Food and drug.

## Regulatory status

- EU: Active — Sorbitan, monooctadecanoate, poly(oxy-1,2-ethanediyl) derivs. (3 mol EO average molar ratio)
- EU: Active — Sorbitan, monooctadecanoate, poly(oxy-1,2-ethanediyl) derivs. (4 mol EO average molar ratio)
- EU: Active — Sorbitan, monooctadecanoate, poly(oxy-1,2-ethanediyl) derivs. (40 mol EO average molar ratio)
- EU: Active — Sorbitan, monooctadecanoate, poly(oxy-1,2-ethanediyl) derivs. (6 mol EO average molar ratio)
- EU: Active — Sorbitan, monooctadecanoate, poly(oxy-1,2-ethanediyl) derivs. (60 mol EO average molar ratio)
- EU: Active — Sorbitan, monooctadecanoate, poly(oxy-1,2-ethanediyl) derivs.
- GLOBAL: Evaluated — JECFA evaluation record.
- US: commercial use observed — EPA CPDat observed this chemical in 2422 composition records across product categories including Personal care, Cleaning and safety, Food and drug. EPA CPDat classifies this chemical for functional uses including Emulsifier, Surfactant (surface active agent), Fragrance.
- US: inactive ingredient database — Route: ORAL; Dosage form: EMULSION; Potency: 20 mg/1ml
- US: inactive ingredient database — Route: ORAL; Dosage form: SUSPENSION; Potency: 25 mg/5ml
- US: inactive ingredient database — Route: ORAL; Dosage form: TABLET, COATED; Potency: NA
- US: inactive ingredient database — Route: RECTAL; Dosage form: SUPPOSITORY; Potency: 0.05 mg/mg
- US: inactive ingredient database — Route: TOPICAL; Dosage form: AEROSOL; Potency: 0.42 %w/w
- US: inactive ingredient database — Route: TOPICAL; Dosage form: AEROSOL, FOAM; Maximum daily exposure: 30 mg
- US: inactive ingredient database — Route: TOPICAL; Dosage form: CREAM; Maximum daily exposure: 225 mg
- US: inactive ingredient database — Route: TOPICAL; Dosage form: LOTION; Potency: 5 %w/w
- US: inactive ingredient database — Route: BUCCAL; Dosage form: GUM, CHEWING; Maximum daily exposure: 5 mg
- US: inactive ingredient database — Route: TOPICAL; Dosage form: SHAMPOO; Potency: 14.55 %w/w
- US: inactive ingredient database — Route: TOPICAL; Dosage form: SUSPENSION; Potency: 2.85 %w/w
- US: inactive ingredient database — Route: VAGINAL; Dosage form: CREAM; Maximum daily exposure: 200 mg
- US: inactive ingredient database — Route: VAGINAL; Dosage form: SUPPOSITORY; Potency: 0.03 mg
- US: marketed drug occurrence — FDA NDC lists this ingredient in 2 active drug products and 3 total products.
- US: listed in openFDA substance — openFDA substance registry classifies this ingredient as polymer.
- US: listed in openFDA substance — openFDA substance registry classifies this ingredient as mixture.
- US: inactive ingredient database — Route: TOPICAL; Dosage form: OINTMENT; Potency: 2 %w/w

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.
- JECFA (Joint FAO/WHO Expert Committee on Food Additives): JECFA evaluation record. — https://apps.who.int/food-additives-contaminants-jecfa-database/Home/Chemical/397.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/58152
- EPA Chemical and Products Database (updated september 28, 2015): http://siri.org/msds/f2/cgj/cgjfz.html
- EPA DSSTox Identifiers (updated 2025-12-29): https://epa.figshare.com/articles/dataset/Chemistry_Dashboard_Data_DSSTox_Identifiers_Mapped_to_CAS_Numbers_and_Names/5588566
- FDA Inactive Ingredient Database (updated 2026-01-09): https://www.fda.gov/drugs/drug-approvals-and-databases/inactive-ingredients-database-download
- FDA National Drug Code Directory (updated 2027-08-05): https://www.fda.gov/drugs/drug-approvals-and-databases/national-drug-code-directory-support-files
- FDA GSRS UNII (updated 2026-02-26): https://precision.fda.gov/uniisearch/
- WHO JECFA Database (updated 2026-10-04): https://apps.who.int/food-additives-contaminants-jecfa-database/Home/Chemical/397
- openFDA Substance (updated 2026-05-24): https://api.fda.gov/other/substance.json?search=unii:073G38N8GC

_Assessed by Greenveil._