What does Propylene glycol diacetate do?

Used in consumer products as a solvent and a flavouring.

Is Propylene glycol diacetate safe?

We haven't assessed a concern score for this ingredient yet.

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Propylene glycol diacetate

CAS 623-84-7

Also registered as 2 other CAS numbers

134236-23-0 · 1432741-27-9

Propylene glycol diacetate chemical structure

Concern score

Not assessed — no hazard data yet.

Propylene glycol diacetate in plain language

What it is: Also known as 1,2-PROPYLENE diacetate · 2-acetyloxypropyl acetate · Pgda · Propane-1,2-diyl diacetate · (+/-)-1,2-Diacetoxypropane · (±)-1,2-DIACETOXYPROPANE
Show all 19 names
1,2-Propanediol, 1,2-diacetate · 1,2-Propanediol, diacetate · 1,2-propandiol diacetate · 1-(acetyloxy)propan-2-yl acetate · 4-02-00-00220 (Beilstein Handbook Reference) · Diacetate, PROPANE-1,2-DIYL · Dowanol PGDA · Ec 210-817-6 · Propyleneglycol diacetate · Propane-1,2-diol diacetate · Propylene glycol di-acetate · UNII-5Z492UNF9O · alpha-Propylene glycol diacetate
What it does: Used in consumer products as a solvent and a flavouring.
Solvent
Flavouring
Is it a concern?: We haven't assessed a concern score for this ingredient yet.

Regulation

No restrictions found. Propylene glycol diacetate appears in these published regulatory listings.

Inactive ingredient in US drugs

Recorded in these product areas

Found in consumer products
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USFDAinactive ingredient database3 entries — 2 administration routes
- Route: AURICULAR (OTIC); Dosage form: SOLUTION; Potency: 3 %w/vSource →
- Route: AURICULAR (OTIC); Dosage form: SOLUTION/ DROPS; Maximum daily exposure: 46 mgSource →
- Route: TOPICAL; Dosage form: CREAM; Potency: 10 %w/wSource →
USEPAcommercial use observedEPA CPDat observed this chemical in 2 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Solvent, Flavouring and nutrient.
- EPA CPDat observed this chemical in 2 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Solvent, Flavouring and nutrient.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Propylene glycol diacetate. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.

Evidence & sources

No graded research studies for Propylene glycol diacetate yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

6 data sources

Where this comes from

EPA Chemical and Products Database
exposure · updated February 8, 2019
Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
Open →
FDA Inactive Ingredient Database
regulatory · updated 2026-01-09
Open →
FDA GSRS UNII
registry · updated 2026-02-26
Open →
openFDA Substance
registry · updated 2026-05-24
Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Open →

Reference links (1)

Openfda substance

thegoodscentscompany.com

Read →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Where it has been recorded

How often EPA CPDat has listed Propylene glycol diacetate in a product composition. These are source records, not Greenveil catalog products.

Source records

Named organisations

Personal care

Typical roles

SolventFlavouring

See products using Propylene glycol diacetate →