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Capryloyl glycine

CAS 14246-53-8 · 0/100 · High conf.

Capryloyl glycine chemical structure

Concern score

0/100Low concern — well-established and permitted without restriction (CIR safe when formulated as directed; EU CosIng).
High confidence

Capryloyl glycine in plain language

What it is

Also known as Glycine, N-(1-oxooctyl)- · 2-(octanoylamino)acetic acid · N-Octanoylglycine · 2-octanamidoacetic acid · Caprylylglycine · Ec 238-122-3

Show all 13 names

Lipacide C 8G · N-(1-oxooctyl)glycine · N-octanoyl-Glycine · UNII-8TY5YO42NJ · capryloyl glycin · capryloylglycine · octanoylglycine

What it does

Used in cosmetics as an antimicrobial, an anti-seborrheic and an anti-sebum. Capryloyl Glycine is the acylation product of glycine with caprylic acid chloride.

  • Antimicrobial
  • Anti-seborrheic
  • Anti-sebum
  • Deodorant
  • Hair conditioning
  • Cleansing
Is it a concern?
Low concern: no hazard classifications on record. It is listed for cosmetic use in the EU.

Why it's flagged

EPA CPDat observed this chemical in 235 composition records across product categories including Personal care, Cleaning products and household care.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Capryloyl glycine appears in these published regulatory listings.

  • In marketed US drugs

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Cleaning
  • EUCosIngActiveCapryloyl Glycine is the acylation product of glycine with caprylic acid chloride. It conforms to the formula:
    • Capryloyl Glycine is the acylation product of glycine with caprylic acid chloride. It conforms to the formula:Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 235 composition records across product categories including Personal care, Cleaning products and household care. EPA CPDat classifies this chemical for functional uses including Surfactant (surface active agent), Cleaning agent, Softener and conditioner.
    • EPA CPDat observed this chemical in 235 composition records across product categories including Personal care, Cleaning products and household care. EPA CPDat classifies this chemical for functional uses including Surfactant (surface active agent), Cleaning agent, Softener and conditioner.Source →
  • USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 2 active drug products and 2 total products.
    • FDA NDC lists this ingredient in 2 active drug products and 2 total products.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Capryloyl glycine. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Capryloyl glycine yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

  • EPA Chemical and Products Database

    exposure · updated September 2013

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA National Drug Code Directory

    regulatory · updated 2027-12-31

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed Capryloyl glycine in a product composition. These are source records, not Greenveil catalog products.

Source records

235

Named organisations

6

Personal careCleaning products and household care

Typical roles

AntimicrobialAnti-seborrheicAnti-sebumDeodorantHair conditioningCleansing
See products using Capryloyl glycine →

Catalog

Found in these products

Cosmetic and personal-care products that list Capryloyl glycine are shown first. Their ingredient lists include Capryloyl glycine; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 100 →Find products without it →