Fragrance avoidance
No fragrance-linked caution surfaced in the current profile.
This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.
CAS 81892-72-0 · 70/100 · High conf.
74918-21-1
Dye · No specific technical function
Concern score
4,4'-[1,3-Propanediylbis(oxy)]bisbenzene-1,3-diamine and its tetrahydrochloride salt (see note 17) is restricted in cosmetic products under Annex III of the EU Cosmetics Regulation (EC) 1223/2009.
RestrictedEU EC — restricted
The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.
Restrictions first, then routine listings from published regulatory sources.
EUEC
2 entries
No graded research studies for Colorex 13bis yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.
EU CosIng Cosmetics Regulation Annexes
regulatory · updated 2013-07-25
EPA Chemical and Products Database
exposure · updated 2019-12-20
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
FDA GSRS UNII
registry · updated 2026-02-26
openFDA Substance
registry · updated 2026-05-24
PubChem Live Enrichment
chemistry · updated 2026-05-17
Context-specific fit derived from published classifications and the current ingredient evidence profile.
Fragrance avoidance
No fragrance-linked caution surfaced in the current profile.
This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.