# 5,6-Dihydroxyindoline

URL: https://app.greenveil.ai/ingredients/ingredient_inci_dihydroxyindoline
Categories: beauty, industrial
Functions: Dye
Identifier: DTXSID80865492

> 5,6-Dihydroxyindoline is used as dye. Greenveil chemical-concern score: 70/100 — High concern based on regulatory listings.. Assessed from 6 sources.

## Safety assessment

- Chemical concern score: 70/100 — High concern based on regulatory listings.
- Confidence: 4
- Rationale: 2,3-Dihydro-1H-indole-5,6-diol and its hydrobromide salt (see note 17). is restricted in cosmetic products under Annex III of the EU Cosmetics Regulation (EC) 1223/2009.

## Regulatory status

- EU: restricted — Annex III of EU Cosmetics Regulation (EC) 1223/2009: substances which cosmetic products must not contain except subject to the restrictions laid down. Product types: Hair dye substance in non-oxidative hair dye products Maximum concentration: 2.0% Conditions of use and warnings: - Can cause allergic reaction - You have ever experienced any reaction afther colouring your hair - You have experienced a reaction to a temporary 'black henna' tattoo in the past
- US: commercial use observed — EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Dye.
- US: listed in openFDA substance — openFDA substance registry classifies this ingredient as chemical.

_Assessed by Greenveil._