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Escherichia coli EXTRACT/SH-POLYPEPTIDE-138

Concern score

Not assessed — no hazard data yet.

Escherichia coli EXTRACT/SH-POLYPEPTIDE-138 in plain language

What it does

Used in cosmetics as a hair conditioner, a hair waving or straightening agent and a surface modifier.

  • Hair conditioning
  • Hair waving or straightening
  • Surface modifier
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

What we know about this ingredient

Canonical ingredient record built from 1 public-source records.

Regulation

No restrictions found. Escherichia coli EXTRACT/SH-POLYPEPTIDE-138 appears in these published regulatory listings.

  • EUCosIngActiveEscherichia Coli Extract/sh-Polypeptide-138 is a single chain recombinant peptide produced by fermentation in E. coli, where the final product contains proteins from the E. coli host. The starting gene, which is a synthesized copy of the human gene that codes for Type II Cuticular Hb5 Keratin, is used as such or adapted to the production host. The parent protein contains a maximum of 507 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.
    • Escherichia Coli Extract/sh-Polypeptide-138 is a single chain recombinant peptide produced by fermentation in E. coli, where the final product contains proteins from the E. coli host. The starting gene, which is a synthesized copy of the human gene that codes for Type II Cuticular Hb5 Keratin, is used as such or adapted to the production host. The parent protein contains a maximum of 507 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.Source →

Expert safety opinions

No expert opinion on file for Escherichia coli EXTRACT/SH-POLYPEPTIDE-138. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Escherichia coli EXTRACT/SH-POLYPEPTIDE-138 yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

1 data source

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.