# ESCHERICHIA COLI EXTRACT/SR-(PROLINYL DI SH-POLYPEPTIDE-145)

URL: https://app.greenveil.ai/ingredients/ingredient_inci_escherichia_coli_extract_sr_prolinyl_di_sh_polypeptide_145
Categories: beauty
Functions: Humectant, Skin conditioning, Hair conditioning, Skin protecting
Identifier: ESCHERICHIA COLI EXTRACT/SR-(PROLINYL DI SH-POLYPEPTIDE-145)

> ESCHERICHIA COLI EXTRACT/SR-(PROLINYL DI SH-POLYPEPTIDE-145): Used in cosmetics as a humectant, a skin-conditioning agent and a hair conditioner. Canonical ingredient record built from 1 public-source records. Compiled from 1 published data source.

## Safety assessment

- Chemical concern: not yet assessed
- Is it a concern? We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
- Rationale: Canonical ingredient record built from 1 public-source records.

## Regulatory status

- EU: Active — Escherichia Coli Extract/sr-(Prolinyl Di sh-Polypeptide-145) is a single chain recombinant peptide produced by fermentation in E. coli, where the final product contains proteins from the E. coli host. The starting gene is synthesized by the fusion of Proline and two repeats of the gene from sh-Polypeptide-145. The fusion peptide contains 17 amino acids which may contain disulfide bonds and/or glycosylation and consists of the proper sequence of the 20 standard amino acids.

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/106869

_Assessed by Greenveil._