# IMMORTALIZED HUMAN TOOTH PULP STEM CELL EXTRACELLULAR VESICLES

URL: https://app.greenveil.ai/ingredients/ingredient_inci_immortalized_human_tooth_pulp_stem_cell_extracellular_vesicles
Categories: beauty
Functions: Humectant, Hair conditioning, Oral care
Identifier: IMMORTALIZED HUMAN TOOTH PULP STEM CELL EXTRACELLULAR VESICLES

> IMMORTALIZED HUMAN TOOTH PULP STEM CELL EXTRACELLULAR VESICLES: Used in cosmetics as a humectant, a hair conditioner and an oral-care ingredient. Canonical ingredient record built from 1 public-source records. Compiled from 1 published data source.

## Safety assessment

- Chemical concern: not yet assessed
- Is it a concern? We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
- Rationale: Canonical ingredient record built from 1 public-source records.

## Regulatory status

- EU: Active — Immortalized Human Tooth Pulp Stem Cell Extracellular Vesicles are the extracellular vesicles secreted by immortalized human tooth pulp stem cells in the media after several days of growth. The cells are immortalized by the insertion of the human papillomavirus E6 and E7 genes, and hTERT gene. The starting media is either Dulbecco's Modified Eagle Medium which may or may not contain fetal bovine serum, or a serum-free nutrient media. Restriction: II/416

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/106359

_Assessed by Greenveil._