# MELIA AZADIRACHTA LEAF

URL: https://app.greenveil.ai/ingredients/ingredient_inci_melia_azadirachta_bark_extract
Categories: beauty, industrial, pharma
Functions: Antimicrobial, Skin conditioning, Skin protecting, Humectant, Conditioner
Identifier: DTXSID901042309

> MELIA AZADIRACHTA LEAF: Used in cosmetics as an antimicrobial, a skin-conditioning agent and a skin protectant. Melia Azadirachta Bark Extract is an extract of the bark of the Neem Tree, Melia azadirachta L., Meliaceae. EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. Compiled from 6 published data sources.

## Safety assessment

- Chemical concern: not yet assessed
- Is it a concern? We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
- Rationale: EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products.

## Regulatory status

- EU: Active — Melia Azadirachta Bark Extract is an extract of the bark of the Neem Tree, Melia azadirachta L., Meliaceae
- EU: Active — Melia Azadirachta Extract is an extract of the Neem Tree, Melia azadirachta L., Meliaceae
- EU: Active — Melia Azadirachta Flower Extract is an extract of the flowers of the Neem Tree, Melia Azadirachta L., Meliaceae
- EU: Active — Melia Azadirachta Leaf is the plant material obtained from the dried leaves of the Neem Tree, Melia azadirachta L., Meliaceae
- US: commercial use observed — EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Biocide, Humectant, Softener and conditioner.
- US: marketed drug occurrence — FDA NDC lists this ingredient in 1 active drug products and 1 total products.
- US: listed in openFDA substance — openFDA substance registry classifies this ingredient as structurallydiverse.

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/57845
- EPA Chemical and Products Database (updated 2019-12-20): https://ec.europa.eu/growth/tools-databases/cosing/index.cfm?fuseaction=search.details_v2&id=57845
- EPA DSSTox Identifiers (updated 2025-12-29): https://epa.figshare.com/articles/dataset/Chemistry_Dashboard_Data_DSSTox_Identifiers_Mapped_to_CAS_Numbers_and_Names/5588566
- FDA National Drug Code Directory (updated 2026-12-31): https://www.fda.gov/drugs/drug-approvals-and-databases/national-drug-code-directory-support-files
- FDA GSRS UNII (updated 2026-02-26): https://precision.fda.gov/uniisearch/
- openFDA Substance (updated 2026-05-24): https://api.fda.gov/other/substance.json?search=unii:P1NV46V59R

_Assessed by Greenveil._