# METHIONYL R-CLOSTRIDIUM BOTULINUM POLYPEPTIDE-1 HEXAPEPTIDE-40

URL: https://app.greenveil.ai/ingredients/ingredient_inci_methionyl_r_clostridium_botulinum_polypeptide_1_hexapeptide_40
Categories: beauty
Functions: Skin protecting
Identifier: METHIONYL R-CLOSTRIDIUM BOTULINUM POLYPEPTIDE-1 HEXAPEPTIDE-40

> METHIONYL R-CLOSTRIDIUM BOTULINUM POLYPEPTIDE-1 HEXAPEPTIDE-40: Used in cosmetics as a skin protectant. Canonical ingredient record built from 1 public-source records. Compiled from 1 published data source.

## Safety assessment

- Chemical concern: not yet assessed
- Is it a concern? We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
- Rationale: Canonical ingredient record built from 1 public-source records.

## Regulatory status

- EU: Active — Methionyl r-Clostridium Botulinum Polypeptide-1 Hexapeptide-40 is a single chain recombinant fusion peptide, produced by fermentation in  E. coli.  The starting gene is synthesized by the fusion of the gene from r-Clostridium Botulinum Polypeptide-1 and Hexapeptide-40 with the initiation codon for methionine. The fusion peptide contains 469 amino acids and consists of the proper sequence of the 20 standard amino acids.

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/93299

_Assessed by Greenveil._