# METHIONYL SH-POLYPEPTIDE-3

URL: https://app.greenveil.ai/ingredients/ingredient_inci_methionyl_sh_polypeptide_3
Categories: beauty
Functions: Skin conditioning
Identifier: METHIONYL SH-POLYPEPTIDE-3

> METHIONYL SH-POLYPEPTIDE-3: Used in cosmetics as a skin-conditioning agent. Canonical ingredient record built from 1 public-source records. Compiled from 1 published data source.

## Safety assessment

- Chemical concern: not yet assessed
- Is it a concern? We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
- Rationale: Canonical ingredient record built from 1 public-source records.

## Regulatory status

- EU: Active — Methionyl sh-Polypeptide-3 is a single chain synthetic peptide, produced by fermentation in E. coli. The starting gene is synthesized by the addition of the initiation codon for methionine with the gene from sh-Polypeptide-3. The peptide contains 164 amino acids which may contain disulfide bonds and/or glycosylation, and consists of the proper sequence of the 20 standard amino acids.

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/105883

_Assessed by Greenveil._