# NEMATODE RH-POLYPEPTIDE-47

URL: https://app.greenveil.ai/ingredients/ingredient_inci_nematode_rh_polypeptide_47
Categories: beauty
Functions: Humectant, Emollient, Skin conditioning
Identifier: NEMATODE RH-POLYPEPTIDE-47

> NEMATODE RH-POLYPEPTIDE-47: Used in cosmetics as a humectant, an emollient and a skin-conditioning agent. Canonical ingredient record built from 1 public-source records. Compiled from 1 published data source.

## Safety assessment

- Chemical concern: not yet assessed
- Is it a concern? We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
- Rationale: Canonical ingredient record built from 1 public-source records.

## Regulatory status

- EU: Active — Nematode rh-Polypeptide-47 is a single chain recombinant human peptide, produced by the nematode,  C. elegans  , after using either a transient expression system or transgenesis (stable insertion of a copy of a human gene into its DNA). The starting gene is directly isolated from a human cell which codes for Collagen Alpha 1. It contains a maximum of 1464 amino acids, which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids Restriction: II/416

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/94298

_Assessed by Greenveil._