# OCTAPEPTIDE-22 R-THERMUS THERMOPHILUS PUTATIVE ESTERASE HEXAPEPTIDE-40

URL: https://app.greenveil.ai/ingredients/ingredient_inci_octapeptide_22_r_thermus_thermophilus_putative_esterase_hexapeptide_40
Categories: beauty
Functions: Skin conditioning
Identifier: OCTAPEPTIDE-22 R-THERMUS THERMOPHILUS PUTATIVE ESTERASE HEXAPEPTIDE-40

> OCTAPEPTIDE-22 R-THERMUS THERMOPHILUS PUTATIVE ESTERASE HEXAPEPTIDE-40: Used in cosmetics as a skin-conditioning agent. Canonical ingredient record built from 1 public-source records. Compiled from 1 published data source.

## Safety assessment

- Chemical concern: not yet assessed
- Is it a concern? We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
- Rationale: Canonical ingredient record built from 1 public-source records.

## Regulatory status

- EU: Active — Octapeptide-22 r-Thermus Thermophilus Putative Esterase Hexapeptide-40 is a single chain recombinant fusion peptide, produced by fermentation in E. coli. The starting gene is synthesized by the fusion of the gene that codes for Thermus Thermophilus Putative Esterase, Octapeptide-22, and Hexapeptide-40. The fused peptide contains 329 amino acids and consists of the proper sequence of the 20 standard amino acids.

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/92133

_Assessed by Greenveil._