# ORYZA SATIVA SH-POLYPEPTIDE-159

URL: https://app.greenveil.ai/ingredients/ingredient_inci_oryza_sativa_sh_polypeptide_159
Categories: beauty
Functions: Emollient, Skin conditioning
Identifier: ORYZA SATIVA SH-POLYPEPTIDE-159

> ORYZA SATIVA SH-POLYPEPTIDE-159: Used in cosmetics as an emollient and a skin-conditioning agent. Canonical ingredient record built from 1 public-source records. Compiled from 1 published data source.

## Safety assessment

- Chemical concern: not yet assessed
- Is it a concern? We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
- Rationale: Canonical ingredient record built from 1 public-source records.

## Regulatory status

- EU: Active — Oryza Sativa sh-Polypeptide-159 is a single chain recombinant peptide produced by Oryza sativa after transformation with either a transient expression system or transgenesis (stable insertion of a copy of the synthetic gene into its DNA). The starting gene is synthesized to be identical to the human gene which codes for Lysosomal acid glucosylceramidase is used as such or adapted to the production host. It contains a maximum of 536 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/104944

_Assessed by Greenveil._