What does Palmitoyl histidyl d-phenylalanyl arginine do?

Used in cosmetics as a skin-conditioning agent. Palmitoyl Histidyl D-Phenylalanyl Arginine is the product obtained by the reaction of palmitic acid and a tripeptide consisting of histidine, D-phenylalanine and arginine.

Is Palmitoyl histidyl d-phenylalanyl arginine safe?

We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

beauty

Palmitoyl histidyl d-phenylalanyl arginine

Concern score

Not assessed — no hazard data yet.

Palmitoyl histidyl d-phenylalanyl arginine in plain language

What it does: Used in cosmetics as a skin-conditioning agent. Palmitoyl Histidyl D-Phenylalanyl Arginine is the product obtained by the reaction of palmitic acid and a tripeptide consisting of histidine, D-phenylalanine and arginine.
Skin conditioning
Is it a concern?: We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

What we know about this ingredient

Canonical ingredient record built from 1 public-source records.

Regulation

No restrictions found. Palmitoyl histidyl d-phenylalanyl arginine appears in these published regulatory listings.

EUCosIngActivePalmitoyl Histidyl D-Phenylalanyl Arginine is the product obtained by the reaction of palmitic acid and a tripeptide consisting of histidine, D-phenylalanine and arginine.
- Palmitoyl Histidyl D-Phenylalanyl Arginine is the product obtained by the reaction of palmitic acid and a tripeptide consisting of histidine, D-phenylalanine and arginine.Source →

Expert safety opinions

No expert opinion on file for Palmitoyl histidyl d-phenylalanyl arginine. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.

Evidence & sources

No graded research studies for Palmitoyl histidyl d-phenylalanyl arginine yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

1 data source

Where this comes from

CosIng
regulatory · updated 2026-09-23
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Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.