# R-(METHIONYL SH-POLYPEPTIDE-9 OLIGOPEPTIDE-164

URL: https://app.greenveil.ai/ingredients/ingredient_inci_r_methionyl_sh_polypeptide_9_oligopeptide_164
Categories: beauty
Functions: Skin conditioning
Identifier: R-(METHIONYL SH-POLYPEPTIDE-9 OLIGOPEPTIDE-164

> R-(METHIONYL SH-POLYPEPTIDE-9 OLIGOPEPTIDE-164: Used in cosmetics as a skin-conditioning agent. Canonical ingredient record built from 2 public-source records. Compiled from 1 published data source.

## Safety assessment

- Chemical concern: not yet assessed
- Is it a concern? We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
- Rationale: Canonical ingredient record built from 2 public-source records.

## Regulatory status

- EU: Active — r-(Methionyl sh-Polypeptide-9 Oligopeptide-164 is a single chain recombinant peptide produced by fermentation in E. coli. The starting gene is synthesized by the fusion of the genes from sh-Polypeptide-9 and Oligopeptide-164 with the initiation codon for methionine. The fusion peptide contains 218 amino acids which may contain disulfide bonds and/or glycolyslation, and consists of the proper sequence of the 20 standard amino acids.
- EU: Active — r-(Methionyl sh-Polypeptide-9 Oligopeptide-164) is a single chain recombinant peptide produced by fermentation in E. coli. The starting gene is synthesized by the fusion of the genes from sh-Polypeptide-9 and Oligopeptide-164 with the initiation codon for methionine. The fusion peptide contains 218 amino acids which may contain disulfide bonds and/or glycolyslation, and consists of the proper sequence of the 20 standard amino acids.

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/104093

_Assessed by Greenveil._