# R-(SH-POLYPEPTIDE-102 SH-POLYPEPTIDE-103)

URL: https://app.greenveil.ai/ingredients/ingredient_inci_r_sh_polypeptide_102_sh_polypeptide_103
Categories: beauty
Functions: Skin protecting
Identifier: R-(SH-POLYPEPTIDE-102 SH-POLYPEPTIDE-103)

> R-(SH-POLYPEPTIDE-102 SH-POLYPEPTIDE-103): Used in cosmetics as a skin protectant. Canonical ingredient record built from 1 public-source records. Compiled from 1 published data source.

## Safety assessment

- Chemical concern: not yet assessed
- Is it a concern? We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
- Rationale: Canonical ingredient record built from 1 public-source records.

## Regulatory status

- EU: Active — R-(sh-Polypeptide-102 sh-Polypeptide-103) is a single chain recombinant peptide, produced by fermentation in E. coli. The starting gene is synthesized by the fusion of the genes encoding for sh-Polypeptide-102 and sh-Polypeptide-103. The fusion peptide contains 282 amino acids which may contain disulfide bonds and/or glycosylation, and consists of the proper sequence of the 20 standard amino acids.

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/95904

_Assessed by Greenveil._