# RH-OLIGOPEPTIDE-2

URL: https://app.greenveil.ai/ingredients/ingredient_inci_rh_oligopeptide_2
Categories: beauty
Functions: Skin protecting
Identifier: RH-OLIGOPEPTIDE-2

> RH-OLIGOPEPTIDE-2: Used in cosmetics as a skin protectant. Canonical ingredient record built from 1 public-source records. Compiled from 1 published data source.

## Safety assessment

- Chemical concern: not yet assessed
- Is it a concern? We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
- Rationale: Canonical ingredient record built from 1 public-source records.

## Regulatory status

- EU: Active — rh-Oligopeptide-2 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene is directly isolated from a human cell which codes for Insulin-Like Growth Factor. It contains a maximum of 153 amino acids which may contain disulfide bonds and/or sugar. The protein consists of the proper sequence of the standard amino acids. Human Oligopeptide-2; IGF-1; Insulin Like Growth Factor; 
Somatomedin C Restriction: II/416

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/85149

_Assessed by Greenveil._