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GREENVEIL

  • beauty

RH-POLYPEPTIDE-104

Concern score

Not assessed — no hazard data yet.

RH-POLYPEPTIDE-104 in plain language

What it is

Also known as Zn-alpha-2-GP

What it does

Used in cosmetics as a skin protectant.

  • Skin protecting
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

What we know about this ingredient

Canonical ingredient record built from 1 public-source records.

Regulation

No restrictions found. RH-POLYPEPTIDE-104 appears in these published regulatory listings.

  • EUCosIngActiverh-Polypeptide-104 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene is directly isolated from a human cell which codes for Zinc-alpha-2-glycoprotein Protein used as such or adapted to the production host. It contains a maximum of 298 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids. Restriction: II/416
    • rh-Polypeptide-104 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene is directly isolated from a human cell which codes for Zinc-alpha-2-glycoprotein Protein used as such or adapted to the production host. It contains a maximum of 298 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids. Restriction: II/416Source →

Expert safety opinions

No expert opinion on file for RH-POLYPEPTIDE-104. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for RH-POLYPEPTIDE-104 yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

1 data source

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.