On cosmetic ingredient lists it appears as “SH-OLIGOPEPTIDE-20 sp”.
Also known as SH-OLIGOPEPTIDE-20 sp · SH-OLIGOPEPTIDE-21 sp · SH-OLIGOPEPTIDE-22 sp · Chemokine TECK
What it does
Used in cosmetics as a skin-conditioning agent.
Skin conditioning
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
What we know about this ingredient
Canonical ingredient record built from 4 public-source records.
Regulation
No restrictions found. RH-POLYPEPTIDE-20 appears in these published regulatory listings.
EU·CosIng·Active4 entries
rh-Polypeptide-20 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene is directly isolated from a human cell which codes for C-C Motif Chemokine 25 used as such or adapted to the production host. It contains a maximum of 150 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids. Restriction: II/416Source →
sh-Oligopeptide-20 SP is a single chain human peptide produced synthetically to be identical to a portion of the protein, C-C Motif Chemokine 25, and contains 21 amino acids consisting of alanine, arginine, aspartic acid, cysteine, glutamic acid, glycine, histidine, isoleucine, leucine, proline, threonine, tryptophan and tyrosine. The parent protein contains a maximum of 150 amino acids which may contain disulfide bonds and/or glycosylation, and consists of the proper sequence of the 20 standard amino acids.Source →
sh-Oligopeptide-21 SP is a single chain human peptide produced synthetically to be identical to a portion of the protein, C-C Motif Chemokine 25, and contains 21 amino acids consisting of alanine, arginine, asparagine, cysteine, glutamic acid, glutamine, glycine, isoleucine, leucine, phenylalanine, proline, serine, threonine and tyrosine. The parent protein contains a maximum of 150 amino acids which may contain disulfide bonds and/or glycosylation, and consists of the proper sequence of the 20 standard amino acids.Source →
sh-Oligopeptide-22 SP is a single chain human peptide produced synthetically to be identical to a portion of the protein, C-C Motif Chemokine 25, and contains 23 amino acids consisting of alanine, arginine, asparagine, aspartic acid, cysteine, glutamic acid, glutamine, glycine, histidine, leucine, lysine, methionine and proline. The parent protein contains a maximum of 150 amino acids which may contain disulfide bonds and/or glycosylation, and consists of the proper sequence of the 20 standard amino acids.Source →
Expert safety opinions
No expert opinion on file for RH-POLYPEPTIDE-20. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.
SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.
Evidence & sources
No graded research studies for RH-POLYPEPTIDE-20 yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.
Context-specific fit derived from published classifications and the current ingredient evidence profile.
Fragrance avoidance
Nothing to weigh for this context yet.
No signal in this context
We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.