RH-POLYPEPTIDE-21

RH-POLYPEPTIDE-21 in plain language

What it is

On cosmetic ingredient lists it appears as “SH-OLIGOPEPTIDE-23 sp”.

Also known as SH-OLIGOPEPTIDE-23 sp · SH-OLIGOPEPTIDE-24 sp · SH-OLIGOPEPTIDE-25 sp · BCA-1,B cell-attracting chemokine 1,CXC chemokine BLC

What it does

Used in cosmetics as a skin-conditioning agent.

• Skin conditioning

Is it a concern?

We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

What we know about this ingredient

Canonical ingredient record built from 4 public-source records.

• EU·CosIng·Active4 entries

  • rh-Polypeptide-21 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene is directly isolated from a human cell which codes for C-X-C Motif Chemokine 13 used as such or adapted to the production host. It contains a maximum of 109 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids. Restriction: II/416Source →
  • sh-Oligopeptide-23 SP is a single chain human peptide produced synthetically to be identical to a portion of the protein, C-X-C Motif Chemokine 13, and contains 25 amino acids consisting of arginine, aspartic acid,cysteine, glutamic acid, glutamine,isoleucine,leucine,phenylalanine and proline. The parent protein contains a maximum of 109 amino acids which may contain disulfide bonds and/or glycosylation, and consists of the proper sequence of the 20 standard amino acids.Source →
  • sh-Oligopeptide-24 SP is a single chain human peptide produced synthetically to be identical to a portion of the protein, C-X-C Motif Chemokine 13, and contains 20 amino acids consisting of arginine, asparagine, cysteine, glutamic acid, glycine, isoleucine, lysine, proline, serine, tryptophan and valine. The parent protein contains a maximum of 109 amino acids which may contain disulfide bonds and/or glycosylation, and consists of the proper sequence of the 20 standard amino acids.Source →
  • sh-Oligopeptide-25 SP is a single chain human peptide produced synthetically to be identical to a portion of the protein, C-X-C Motif Chemokine 13, and contains 19 amino acids consisting of alanine, arginine, aspartic acid, cysteine, glutamic acid, glutamine, isoleucine, leucine, lysine, methionine, proline, tryptophan and valine. The parent protein contains a maximum of 109 amino acids which may contain disulfide bonds and/or glycosylation, and consists of the proper sequence of the 20 standard amino acids.Source →

Expert safety opinions

No expert opinion on file for RH-POLYPEPTIDE-21. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

• SCCS

  EU Scientific Committee on Consumer Safety

  No SCCS opinion on file.

• CIR

  Cosmetic Ingredient Review (US expert panel)

  No CIR safety assessment on file.