# S-SPIDER PENTAPEPTIDE-2

URL: https://app.greenveil.ai/ingredients/ingredient_inci_s_spider_pentapeptide_2
Categories: beauty
Functions: Skin conditioning
Identifier: S-SPIDER PENTAPEPTIDE-2

> S-SPIDER PENTAPEPTIDE-2: Used in cosmetics as a skin-conditioning agent. Canonical ingredient record built from 1 public-source records. Compiled from 1 published data source.

## Safety assessment

- Chemical concern: not yet assessed
- Is it a concern? We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
- Rationale: Canonical ingredient record built from 1 public-source records.

## Regulatory status

- EU: Active — s-Spider Pentapeptide-2 is a single chain peptide consisting of glycine, glutamine, and proline. It is synthetically produced based on a sequence from Spidroin 2 found in the spider, Nephila clavipes. The parent protein contains a maximum of 627 amino acids which may contain disulfide bonds and/or glycosylation, and consists of the proper sequence from the 20 standard amino acids.

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/100780

_Assessed by Greenveil._