# SH-DECAPEPTIDE-3

URL: https://app.greenveil.ai/ingredients/ingredient_inci_sh_decapeptide_3
Categories: beauty
Functions: Antimicrobial, Antioxidant, Humectant, Skin conditioning, Bleaching, Hair conditioning
Identifier: SH-DECAPEPTIDE-3

> SH-DECAPEPTIDE-3: Used in cosmetics as an antimicrobial, an antioxidant and a humectant. Canonical ingredient record built from 4 public-source records. Compiled from 1 published data source.

## Safety assessment

- Chemical concern: not yet assessed
- Is it a concern? We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
- Rationale: Canonical ingredient record built from 4 public-source records.

## Regulatory status

- EU: Active — sh-Decapeptide-3 is a single chain human peptide produced synthetically to be identical to a portion of the protein Metastasis-suppressor KiSS-1, and contains 10 amino acids consisting of arginine, asparagine, glycine, leucine, phenylalanine, serine, tryptophan and tyrosine. The parent protein contains a maximum of 138 amino acids which may contain disulfide bonds and/or glycosylation, and consists of the proper sequence of the 20 standard amino acids.
- EU: Active — sh-Decapeptide-3 Amide is a sh-Decapeptide-3 in which the C-terminus of the peptide is an amide.
- EU: Active — sh-Pentapeptide-9 is a single chain human peptide produced synthetically to be identical to a portion of the protein, Metastasis-suppressor KiSS-1, and contains 5 amino acids consisting of asparagine, serine, tryptophan and tyrosine.
- EU: Active — sh-Pentapeptide-9 SP Amide is sh-Pentapeptide-9 in which the C-terminus is an amide.

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/96316

_Assessed by Greenveil._