# SH-HEPTAPEPTIDE-18

URL: https://app.greenveil.ai/ingredients/ingredient_inci_sh_heptapeptide_18
Categories: beauty
Functions: Antioxidant, Anti-sebum, Skin protecting
Identifier: SH-HEPTAPEPTIDE-18

> SH-HEPTAPEPTIDE-18: Used in cosmetics as an antioxidant, an anti-sebum and a skin protectant. Canonical ingredient record built from 2 public-source records. Compiled from 1 published data source.

## Safety assessment

- Chemical concern: not yet assessed
- Is it a concern? We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
- Rationale: Canonical ingredient record built from 2 public-source records.

## Regulatory status

- EU: Active — sh-Heptapeptide-18 is a single chain human peptide produced synthetically to be identical to a portion of the protein, Dynorphin A, and contains 7 amino acids consisting of arginine, glycine, leucine, phenylalanine, and tyrosine
- EU: Active — sh-Octapeptide-16 is a single chain human peptide produced synthetically to be identical to a portion of the protein, Dynorphin A and contains 8 amino acids consisting of arginine, glycine, isoleucine, leucine, phenylalanine, and tyrosine.

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/90805

_Assessed by Greenveil._