# SH-OLIGOPEPTIDE-108 SP

URL: https://app.greenveil.ai/ingredients/ingredient_inci_sh_oligopeptide_108_sp
Categories: beauty
Functions: Skin conditioning, Skin protecting
Identifier: SH-OLIGOPEPTIDE-108 SP

> SH-OLIGOPEPTIDE-108 SP: Used in cosmetics as a skin-conditioning agent and a skin protectant. Canonical ingredient record built from 1 public-source records. Compiled from 1 published data source.

## Safety assessment

- Chemical concern: not yet assessed
- Is it a concern? We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
- Rationale: Canonical ingredient record built from 1 public-source records.

## Regulatory status

- EU: Active — sh-Oligopeptide-108 SP is a single chain human peptide produced synthetically to be identical to a portion of the protein, Beta Defensin 103, and contains 45 amino acids consisting of alanine, arginine, asparagine, cysteine, glutamic acid, glutamine, glycine, isoleucine, leucine, lysine, proline, serine, threonine, tyrosine and valine. Beta Defensin 103 contains 67 amino acids which may contain disulfide bonds and/or glycosylation. It consists of the proper sequence from the 20 standard amino acids.

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/100836

_Assessed by Greenveil._