# SH-OLIGOPEPTIDE-111 SP AMIDE

URL: https://app.greenveil.ai/ingredients/ingredient_inci_sh_oligopeptide_111_sp_amide
Categories: beauty
Functions: Skin conditioning
Identifier: SH-OLIGOPEPTIDE-111 SP AMIDE

> SH-OLIGOPEPTIDE-111 SP AMIDE: Used in cosmetics as a skin-conditioning agent. Canonical ingredient record built from 1 public-source records. Compiled from 1 published data source.

## Safety assessment

- Chemical concern: not yet assessed
- Is it a concern? We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
- Rationale: Canonical ingredient record built from 1 public-source records.

## Regulatory status

- EU: Active — sh-Oligopeptide-111 SP Amide is a single chain human peptide produced synthetically to be identical to a portion of the protein, Natriuretic Peptide, and contains 26 amino acids consisting of arginine, aspartic acid, cysteine, glutamine, glycine, isoleucine, leucine, lysine, methionine, phenylalanine, proline, serine and valine in which the C-terminus is an amide. Natriuretic Peptide contains a maximum of 134 amino acids which may contain disulfide bonds and/or glycosylation. It consists of the proper sequence of the 20 standard amino acids.

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/101691

_Assessed by Greenveil._