# SH-OLIGOPEPTIDE-127 SP

URL: https://app.greenveil.ai/ingredients/ingredient_inci_sh_oligopeptide_127_sp
Categories: beauty
Functions: Skin conditioning, Hair conditioning, Skin protecting
Identifier: SH-OLIGOPEPTIDE-127 SP

> SH-OLIGOPEPTIDE-127 SP: Used in cosmetics as a skin-conditioning agent, a hair conditioner and a skin protectant. Canonical ingredient record built from 1 public-source records. Compiled from 1 published data source.

## Safety assessment

- Chemical concern: not yet assessed
- Is it a concern? We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
- Rationale: Canonical ingredient record built from 1 public-source records.

## Regulatory status

- EU: Active — sh-Oligopeptide-127 SP is a single chain human peptide produced synthetically to be identical to a portion of the protein, Mitochondrial-derived peptide MOTS-c, and contains 16 amino acids consisting of arginine, glutamic acid, glutamine, glycine, isoleucine, leucine, lysine, methionine, phenylalanine, proline, tryptophan and tyrosine. Mitochondrial-derived peptide MOTS-c contains a maximum of 16 amino acids which may contain disulfide bonds and/or glycosylation. It consists of the proper sequence of the 20 standard amino acids.

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/104974

_Assessed by Greenveil._