Fragrance avoidance
Nothing to weigh for this context yet.
We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.
- beauty
SH-OLIGOPEPTIDE-281 sp
Concern score
Not assessed — no hazard data yet.
SH-OLIGOPEPTIDE-281 sp in plain language
Used in cosmetics as a hair conditioner, a hair fixative and a hair waving or straightening agent.
- Hair conditioning
- Hair fixing
- Hair waving or straightening
- We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
What we know about this ingredient
Canonical ingredient record built from 1 public-source records.
Regulation
No restrictions found. SH-OLIGOPEPTIDE-281 sp appears in these published regulatory listings.
EUCosIngActivesh-Oligopeptide-281 SP is a single chain human peptide produced synthetically and inspired by the protein, Human Pulmonary Surfactant-Associated Protein D, and contains 23 amino acids consisting of alanine, cysteine, glutamic acid, glutamine, glycine, histidine, leucine, lysine, phenylalanine, proline, serine, tyrosine and valine. Human Pulmonary Surfactant-Associated Protein D contains a maximum of 237 amino acids which may contain disulfide bonds and/or glycosylation. It consists of the proper sequence of the 20 standard amino acids.
- sh-Oligopeptide-281 SP is a single chain human peptide produced synthetically and inspired by the protein, Human Pulmonary Surfactant-Associated Protein D, and contains 23 amino acids consisting of alanine, cysteine, glutamic acid, glutamine, glycine, histidine, leucine, lysine, phenylalanine, proline, serine, tyrosine and valine. Human Pulmonary Surfactant-Associated Protein D contains a maximum of 237 amino acids which may contain disulfide bonds and/or glycosylation. It consists of the proper sequence of the 20 standard amino acids.Source →
Expert safety opinions
No expert opinion on file for SH-OLIGOPEPTIDE-281 sp. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.
SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.
Evidence & sources
No graded research studies for SH-OLIGOPEPTIDE-281 sp yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.
Where this comes from
- Open →
CosIng
regulatory · updated 2026-09-23
Suitability
Context-specific fit derived from published classifications and the current ingredient evidence profile.
No signal in this context