# SH-OLIGOPEPTIDE-281 SP

URL: https://app.greenveil.ai/ingredients/ingredient_inci_sh_oligopeptide_281_sp
Categories: beauty
Functions: Hair conditioning, Hair fixing, Hair waving or straightening
Identifier: SH-OLIGOPEPTIDE-281 SP

> SH-OLIGOPEPTIDE-281 SP: Used in cosmetics as a hair conditioner, a hair fixative and a hair waving or straightening agent. Canonical ingredient record built from 1 public-source records. Compiled from 1 published data source.

## Safety assessment

- Chemical concern: not yet assessed
- Is it a concern? We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
- Rationale: Canonical ingredient record built from 1 public-source records.

## Regulatory status

- EU: Active — sh-Oligopeptide-281 SP is a single chain human peptide produced synthetically and inspired by the protein, Human Pulmonary Surfactant-Associated Protein D, and contains 23 amino acids consisting of alanine, cysteine, glutamic acid, glutamine, glycine, histidine, leucine, lysine, phenylalanine, proline, serine, tyrosine and valine. Human Pulmonary Surfactant-Associated Protein D contains a maximum of 237 amino acids which may contain disulfide bonds and/or glycosylation. It consists of the proper sequence of the 20 standard amino acids.

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/105682

_Assessed by Greenveil._