# SH-OLIGOPEPTIDE-35 SP

URL: https://app.greenveil.ai/ingredients/ingredient_inci_sh_oligopeptide_35_sp
Categories: beauty
Functions: Antimicrobial, Skin conditioning
Identifier: SH-OLIGOPEPTIDE-35 SP

> SH-OLIGOPEPTIDE-35 SP: Used in cosmetics as an antimicrobial and a skin-conditioning agent. Canonical ingredient record built from 1 public-source records. Compiled from 1 published data source.

## Safety assessment

- Chemical concern: not yet assessed
- Is it a concern? We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
- Rationale: Canonical ingredient record built from 1 public-source records.

## Regulatory status

- EU: Active — sh-Oligopeptide-35 SP is a single chain human peptide produced synthetically to be identical to a portion of the protein, Defensin Beta 4A and contains 25 amino acids consisting of arginine, cysteine, glutamine, glycine, isoleucine, leucine, lysine, phenylalanine, proline, threonine, tyrosine and valine. Defensin Beta 4A contains a maximum of 109 amino acids which may contain disulfide bonds and/or glycosylation. It consists of the proper sequence from the 20 standard amino acids.

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/101653

_Assessed by Greenveil._