# SH-OLIGOPEPTIDE-81 AMIDE

URL: https://app.greenveil.ai/ingredients/ingredient_inci_sh_oligopeptide_81_amide
Categories: beauty
Functions: Antimicrobial, Humectant, Anti-sebum, Antiplaque, Oral care
Identifier: SH-OLIGOPEPTIDE-81 AMIDE

> SH-OLIGOPEPTIDE-81 AMIDE: Used in cosmetics as an antimicrobial, a humectant and an anti-sebum. Canonical ingredient record built from 1 public-source records. Compiled from 1 published data source.

## Safety assessment

- Chemical concern: not yet assessed
- Is it a concern? We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
- Rationale: Canonical ingredient record built from 1 public-source records.

## Regulatory status

- EU: Active — sh-Oligopeptide-81 Amide is a 14 amino acid protein fragment in which the C-terminus of the peptide is an amide, and it is produced synthetically to be identical to a fragment of the human protein, Histatin-3.

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/93921

_Assessed by Greenveil._