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GREENVEIL

  • beauty

SH-POLYPEPTIDE-177 TRIPEPTIDE-46 HEXAPEPTIDE-40

Concern score

Not assessed — no hazard data yet.

SH-POLYPEPTIDE-177 TRIPEPTIDE-46 HEXAPEPTIDE-40 in plain language

What it does

Used in cosmetics as a skin-conditioning agent, a hair conditioner and a skin protectant.

  • Skin conditioning
  • Hair conditioning
  • Skin protecting
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

What we know about this ingredient

Canonical ingredient record built from 1 public-source records.

Regulation

No restrictions found. SH-POLYPEPTIDE-177 TRIPEPTIDE-46 HEXAPEPTIDE-40 appears in these published regulatory listings.

  • EUCosIngActivesh-Polypeptide-177 Tripeptide-46 Hexapeptide-40 is a single chain synthetic fusion peptide, produced by fermentation in Pichia. The starting gene is synthesized by the fusion of the gene from sh-Polypeptide-177, Tripeptide-46, and Hexapeptide-40. The fusion peptide contains 40 amino acids which may contain disulfide bonds and/or glycosylation, and consists of the proper sequence of the 20 standard amino acids.
    • sh-Polypeptide-177 Tripeptide-46 Hexapeptide-40 is a single chain synthetic fusion peptide, produced by fermentation in Pichia. The starting gene is synthesized by the fusion of the gene from sh-Polypeptide-177, Tripeptide-46, and Hexapeptide-40. The fusion peptide contains 40 amino acids which may contain disulfide bonds and/or glycosylation, and consists of the proper sequence of the 20 standard amino acids.Source →

Expert safety opinions

No expert opinion on file for SH-POLYPEPTIDE-177 TRIPEPTIDE-46 HEXAPEPTIDE-40. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for SH-POLYPEPTIDE-177 TRIPEPTIDE-46 HEXAPEPTIDE-40 yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

1 data source

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.