# SH-POLYPEPTIDE-56 RH-POLYPEPTIDE-65

URL: https://app.greenveil.ai/ingredients/ingredient_inci_sh_polypeptide_56_rh_polypeptide_65
Categories: beauty
Functions: Skin conditioning, Hair conditioning, Skin protecting
Identifier: SH-POLYPEPTIDE-56 RH-POLYPEPTIDE-65

> SH-POLYPEPTIDE-56 RH-POLYPEPTIDE-65: Used in cosmetics as a skin-conditioning agent, a hair conditioner and a skin protectant. Canonical ingredient record built from 1 public-source records. Compiled from 1 published data source.

## Safety assessment

- Chemical concern: not yet assessed
- Is it a concern? We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
- Rationale: Canonical ingredient record built from 1 public-source records.

## Regulatory status

- EU: Active — sh-Polypeptide-56 rh-Polypeptide-65 is a single chain synthetic fusion peptide, produced by fermentation in E. coli. The starting gene is synthesized by the fusion of the gene from sh-Polypeptide-56 and rh-Polypeptide-65 . The fused peptide contains 1104 amino acids and consists of the proper sequence of the 20 standard amino acids. Restriction: II/416

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/90085

_Assessed by Greenveil._