# SILKWORM SH-POLYPEPTIDE-69

URL: https://app.greenveil.ai/ingredients/ingredient_inci_silkworm_sh_polypeptide_69
Categories: beauty
Functions: Humectant, Skin conditioning
Identifier: SILKWORM SH-POLYPEPTIDE-69

> SILKWORM SH-POLYPEPTIDE-69: Used in cosmetics as a humectant and a skin-conditioning agent. Canonical ingredient record built from 1 public-source records. Compiled from 1 published data source.

## Safety assessment

- Chemical concern: not yet assessed
- Is it a concern? We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
- Rationale: Canonical ingredient record built from 1 public-source records.

## Regulatory status

- EU: Active — Silkworm sh-Polypeptide-69 is a single chain recombinant human peptide, produced by silkworm after after using either a transient expression system or transgenesis (stable insertion of a copy of a human gene into its DNA). The starting gene is synthesized to be identical to the human gene which codes for Collagen Alpha-1 (III) Chain. It contains a maximum of 1466 amino acids, which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/96695

_Assessed by Greenveil._