# SR-(DECAPEPTIDE-63 SH-POLYPEPTIDE-148 HEXAPEPTIDE-40)

URL: https://app.greenveil.ai/ingredients/ingredient_inci_sr_decapeptide_63_sh_polypeptide_148_hexapeptide_40
Categories: beauty
Functions: Skin conditioning
Identifier: SR-(DECAPEPTIDE-63 SH-POLYPEPTIDE-148 HEXAPEPTIDE-40)

> SR-(DECAPEPTIDE-63 SH-POLYPEPTIDE-148 HEXAPEPTIDE-40): Used in cosmetics as a skin-conditioning agent. Canonical ingredient record built from 1 public-source records. Compiled from 1 published data source.

## Safety assessment

- Chemical concern: not yet assessed
- Is it a concern? We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
- Rationale: Canonical ingredient record built from 1 public-source records.

## Regulatory status

- EU: Active — sr-(Decapeptide-63 sh-Polypeptide-148 Hexapeptide-40) is a single chain recombinant peptide, produced by fermentation in Pichia pastoris. The starting gene is synthesized by the fusion of the gene from sh-Polypeptide-148, Hexapeptide-40, and Decapeptide-63 which contains a Strep-tag sequence. The fusion peptide contains 249 amino acids which may contain disulfide bonds and/or glycosylation and consists of the proper sequence of the 20 standard amino acids.

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/101646

_Assessed by Greenveil._