# SR-(ESCHERICHIA COLI METHIONYL HEXAPEPTIDE-40 SPIDER POLYPEPTIDE-3) FERMENT EXTRACT

URL: https://app.greenveil.ai/ingredients/ingredient_inci_sr_escherichia_coli_methionyl_hexapeptide_40_spider_polypeptide_3_ferment_extract
Categories: beauty
Functions: Skin conditioning, Hair conditioning, Skin protecting, Film forming
Identifier: SR-(ESCHERICHIA COLI METHIONYL HEXAPEPTIDE-40 SPIDER POLYPEPTIDE-3) FERMENT EXTRACT

> SR-(ESCHERICHIA COLI METHIONYL HEXAPEPTIDE-40 SPIDER POLYPEPTIDE-3) FERMENT EXTRACT: Used in cosmetics as a skin-conditioning agent, a hair conditioner and a skin protectant. Canonical ingredient record built from 1 public-source records. Compiled from 1 published data source.

## Safety assessment

- Chemical concern: not yet assessed
- Is it a concern? We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
- Rationale: Canonical ingredient record built from 1 public-source records.

## Regulatory status

- EU: Active — sr-(Escherichia Coli Methionyl Hexapeptide-40 Spider Polypeptide-3) Ferment Extract is the extract of a single chain fusion peptide, produced by fermentation in E. coli. The starting gene is synthesized by the fusion of the gene which is similar to sr-Spider Polypeptide-3, with Hexapeptide-40, and the initiation code for Methionine. The fusion peptide contains 1760 amino acids which may contain disulfide bonds and/or glycosylation, and consists of the proper sequence of the 20 standard amino acids.

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/99711

_Assessed by Greenveil._