# SR-(METHIONYL HEXAPEPTIDE-40 SACCHAROMYCES POLYPEPTIDE-2 SH-POLYPEPTIDE-134)

URL: https://app.greenveil.ai/ingredients/ingredient_inci_sr_methionyl_hexapeptide_40_saccharomyces_polypeptide_2_sh_polypeptide_134
Categories: beauty
Functions: Emollient
Identifier: SR-(METHIONYL HEXAPEPTIDE-40 SACCHAROMYCES POLYPEPTIDE-2 SH-POLYPEPTIDE-134)

> SR-(METHIONYL HEXAPEPTIDE-40 SACCHAROMYCES POLYPEPTIDE-2 SH-POLYPEPTIDE-134): Used in cosmetics as an emollient. Canonical ingredient record built from 1 public-source records. Compiled from 1 published data source.

## Safety assessment

- Chemical concern: not yet assessed
- Is it a concern? We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
- Rationale: Canonical ingredient record built from 1 public-source records.

## Regulatory status

- EU: Active — sr-(Methionyl Hexapeptide-40 Saccharomyces Polypeptide-2 sh-Polypeptide-134) is a single chain recombinant peptide, produced by fermentation in E. coli. The starting gene is synthesized by the fusion of the genes from Hexapeptide-40, r-Saccharomyces Polypeptide-2, and sh-Polypeptide-134 with the initiation codon for methionine. The fusion peptide may contain disulfide bonds and/or glycosylation, and consists of the proper sequence of the 20 standard amino acids

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/100183

_Assessed by Greenveil._