# SR-(SH-POLYPEPTIDE-140 SH-POLYPEPTIDE-141 SH-POLYPEPTIDE-142)

URL: https://app.greenveil.ai/ingredients/ingredient_inci_sr_sh_polypeptide_140_sh_polypeptide_141_sh_polypeptide_142
Categories: beauty
Functions: Antimicrobial
Identifier: SR-(SH-POLYPEPTIDE-140 SH-POLYPEPTIDE-141 SH-POLYPEPTIDE-142)

> SR-(SH-POLYPEPTIDE-140 SH-POLYPEPTIDE-141 SH-POLYPEPTIDE-142): Used in cosmetics as an antimicrobial. Canonical ingredient record built from 1 public-source records. Compiled from 1 published data source.

## Safety assessment

- Chemical concern: not yet assessed
- Is it a concern? We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.
- Rationale: Canonical ingredient record built from 1 public-source records.

## Regulatory status

- EU: Active — sr-(sh-Polypeptide-140 sh-Polypeptide-141 sh-Polypeptide-142) is a single chain recombinant peptide, produced by fermentation in Chinese hamster ovary cells. The starting gene is synthesized by the fusion of the gene from sh-Polypeptide-140, sh-Polypeptide-141, and sh-Polypeptide-142. The fusion peptide contains 494 amino acids which may contain disulfide bonds and/or glycosylation, and consists of the proper sequence of the 20 standard amino acids.

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/101059

_Assessed by Greenveil._